Hi,
at first, connect the VP-727 via serial cable to the RS-232C port of Your PC, of course

The next thing is to configure the RS232 port. Open General Options>Permanent Options>RS232 Control, check the used port for outgoing communication (RS232 Out) and adjust the parameters for the port (see Your VP-727 manual p. 39, right below the example). Press OK if done.
Now, for testing, create a new production, add a control cue within the editor and select RS232 as message type. Leave RS232device as RS232 and Entry mode as ASCII and keep "Add CR (0DH) to end of RS232 Message?" checked. Enter the message to be tested like in the given example (the black squares mean "Space", just hit space bar ), take the exact commands from Table 17 from next page. You don't need to add the CR, SCS will do this for You. Click "Test Control Message" and see if it works
Have fun
Jörg